The project aims to reduce inappropriate polypharmacy and optimise medicines for patients in the Solihull Locality. Solihull CCG (now merged with other CCGs to form Birmingham and Solihull CCG) has 25 member GP practices/partnerships with a population of approximately 240,000 patients.
Inappropriate polypharmacy is defined by NICE as 'prescribing of multiple medicines inappropriately, or where the intended benefit of the medicines are not realised'1. It has been well documented that the number of patients with polypharmacy is ever increasing, as life expectancy has increased and there are more patients with multimorbidities. Inappropriate polypharmacy has seen a rise and there is evidence to show that it can lead to increased risk of adverse effects and potential hospital admissions. There is also a significant cost burden to the NHS to fund treatments which may no longer be appropriate. As a side product we would hope to reduce hospital admissions, promote cost-effective, evidence-based prescribing and produce significant cost savings to prescribing budgets (CCG and NHS).1,2,3
Prior to this project, GPs were doing their own polypharmacy reviews with assistance from Prescribing Support Pharmacists (PSPs), as a part of their contracted Local Improvement Scheme (LIS) with the CCG. It was found over time, that the reviews the PSPs did were of higher quality with more clinical interventions and cost savings. A business case was put forward at STP level for the recruitment of additional pharmacists to carry out medication reviews in practices. This would reduce pressure on GPs to do the reviews and aim to produce further positive outcomes from pharmacist reviews. Using their allocation, Solihull CCG recruited two fixed-term Medication Review Pharmacists (MRPs) at Band 7 level with a two-year contract. They were tasked with completing approximately 30 reviews a week (1000 a year) for practices in the Solihull locality. The medication review process was tailored to each individual practice and done in the way best suited to them (see Appendix 1 - Polypharmacy Proforma). The Practices were asked how they wanted the reviews to be delivered and the MRPs did their best to facilitate them. Each practice had to do reviews on 2% of their baseline population, as per their contract, and the MRPs were to support them with this.
The MRPs targeted elderly patients on the highest number of medicines and raised any issues with the GPs e.g. drug interactions, discharge discrepancies, dose optimisations and overdue monitoring. The reviews were mostly paper-based (with some phone consultations when agreed with GP), and suggestions were made by MRPs which the GPs actioned within the agreed timeframe. Interventions and savings are then recorded once any actions have been completed. Most of the practices agreed to allow remote access to their clinical systems (from the CCG base) which increased efficiency and saved the MRPs travel time, as they were not dependant on room availability at the practices. This allowed them to produce more reviews in a shorter space of time and increase the number of outcomes they achieved. Some of the resources used include: PrescQIPP polypharmacy and deprescribing webkit, King's Fund STOPP/START tool, IMPACT tool, NICE Evidence and Guidelines, Local CCG guidelines and APC formulary.
The main beneficiaries of the project would be the patients and their carers. With reduced polypharmacy they would hopefully have an improved quality of life with a decreased tablet burden, reduced risk of adverse effects and hospital admissions and optimisation of their medicines4. The GPs and prescribers would also benefit from the pharmaceutical knowledge and expertise of pharmacists. They can pick up things that may have been missed and provide information using the latest guidance and evidence. This helps educate and influence the GPs to positively change their prescribing habits and benefit other/future patients. Practices benefit from reduced drug expenditure, positive patient outcomes and potential decreased hospital admissions for their QoF Framework. The CCG as a commissioning group also benefit from improved patient outcomes in the locality and improved drug budgets.
Between July 2017 and April 2018, the MRPs completed 1207 reviews and made 2113 interventions. 1172 (56%) of these interventions were clinical interventions (dose changes, medication stopped/started) and 196 (9%) were potential admission preventions. (For break down and intervention definitions see supporting document 2).
Clinical interventions included:
Drug cost savings (over 12months) totalled £132,382.91 for 2 WTE MRPs, at an average of £109.68 saving per patient reviewed. These savings reduce pressures on practice prescribing budgets and promote cost-effective prescribing.
Feedback from GPs included:
Feedback from Patients included:
As entry level band 7s they have a total wage of approximately £63k a year full time and have managed to save more than double that (from drug-cost savings) in 9 months, which shows that they have been cost effective to employ. The CCG is also now considering a business case to make the MRPs permanent.